• Opsin Lens •
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Introduction
Sitting at the back of the Opsin Portal, a lens is shaped like a shallow bowl. This is the:
Inner Lens
The Inner Lens sits in the middle of Lamina. Supporting the Opsin Portal, the Opsin Rings and Ixchel.
Biology
Neural Plate in Neurogenesis
Formation of Neural Plate:
The ectoderm receives signals from the notochord (mainly BMP inhibitors like Noggin, Chordin)
These signals induce a region of ectoderm to become neuroectoderm → this thickened area is the neural plate
Neural Plate as a Source of Neural Progenitors:
The cells of the neural plate are neuroepithelial cells, which are multipotent progenitors
Transition to Neural Tube
The neural plate folds into the neural tube
Neuroepithelial cells in the neural tube start differentiating into neurons in a highly organized sequence:
Apical-basal polarity is established
Symmetric divisions expand the progenitor pool
Asymmetric divisions produce one progenitor + one neuron or intermediate progenitor
Contribution to CNS and Neural Crest
Neural crest cells (from neural plate edges) → peripheral nervous system, Schwann cells, sensory neurons
neural plate isn’t just a structure—it’s the launchpad for neurogenesis, determining the fate and organization of future neurons
Neural plate = early neuroepithelium → source of neural stem cells
Induced by BMP inhibitors from notochord
Folds to form neural tube → neurogenesis proper begins
Neural plate edges = neural crest → peripheral neurogenesis
Neural plate border → neural crest cells → migration → PNS components
