Fate Determination

Second Loop

Fate determination is when a young brain cell decides what it will become.

What controls fate determination?

Signals from the environment

Key signaling pathways:

Notch

Wnt

BMP

Certain genes turn on while others turn off, locking in the choice

Differentiation

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Migration

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Neurite Outgrowth

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Synaptogenesis

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Maturation

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