• Creation •
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Law Of The Living
The closest thing Lamina has to world religions is the Law Of The Living. A collection of four books of instruction to build the world
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Book 1
The First Creation
Outside of the borders of the universe. A space exists between two “Parent Systems” creating a system of three linear types of input.This is the main blueprint.
Nuclumito reads the differences between the two “Parents” to create a short, compact linear sequence of events. Acceptor Stem being the receiver of tRNA / Amino Acids in the sequence
Book 1:2
When linear events have reached an end, it then evolves into “animal loops”: Anticodon loop, the Variable loop and the TψC loop.
A three ring system that demands the tRNA codes for a species as one “Parent”
A Variable Loop specific to a species
TψC loop - Opposite of the Anticodon Loop
When 7S DNA forms:
7S DNA synthesis begins at:
OH (Origin of Heavy-Strand Replication)
origin of replication is:
A specific DNA sequence where DNA copying begins.
Replication begins at OH
RNA polymerase creates a short RNA primer.
DNA polymerase γ begins synthesizing a new heavy strand.
The new strand displaces the old H-strand
Replication proceeds around the circular mtDNA molecule.
OL becomes exposed
When replication reaches about 2/3 of the circle, another origin appears:
OL (Origin of Light-Strand Replication)
At that point, replication of the light strand begins in the opposite direction
Initiated at OH
Continued until OL is activated
Completed when both strands finish
OH
It regulates mitochondrial DNA copy number
It controls replication timing
Mutations here can disrupt mitochondrial function
It lies in the D-loop, the most mutation-prone region
OH works with:
DNA polymerase γ
TWINKLE helicase
mtSSB (mitochondrial single-strand binding protein)
Transcription machinery in the D-loop
The exact nucleotide sequence of OH is different between species
RNA polymerase lays down a primer.
DNA polymerase γ extends it.
Then synthesis stops early.
It does NOT complete the full circle.
Termination Region
7S DNA typically stops near:
Conserved Sequence Blocks (CSB I, II, III)
Replication in mitochondria is asymmetric:
Heavy strand starts first
Light strand starts later at a separate site (outside the control region)
Promoters
two main promoters:
HSP (Heavy Strand Promoter)
Starts transcription of the heavy strand
LSP (Light Strand Promoter)
Starts transcription of the light strand
Also helps initiate replication
Conserved Sequence Blocks (CSBs)
Short DNA sequences important for replication
Help regulate primer formation for DNA synthesis
Usually labeled:
CSB I
CSB II
CSB III
Hypervariable Regions (HVRs)
Often called:
HVR1
HVR2
Sometimes HVR3
iris
sits between:
The cornea (front clear dome)
The lens
Anterior Border Layer
the front surface of the iris
Made of fibroblasts (connective tissue cells)
Contains melanocytes (pigment cells)
Gives the iris its textured appearance (crypts and ridges)
Stroma
is the thick middle layer of the iris
stroma gives the iris its depth and pattern complexity.
Iris Muscles
muscles that control pupil size
Sphincter Pupillae
Located near the pupil edge
Arranged in a circular ring
Constricts the pupil (miosis)
Activated by the parasympathetic nervous system
Dilator Pupillae
Dilates the pupil (mydriasis)
Activated by the sympathetic nervous system
Posterior Pigment Epithelium
back layer of the iris.
Structure:
Two layers of heavily pigmented epithelial cells
Function:
Prevents light from passing through the iris tissue
Ensures light only enters via the pupil
Enhances image clarity
Pupil
an opening in the center of the iris.
Collarette
A circular ridge about 1.5 mm from the pupil
Thickest part of the iris
Divides the iris into:
Pupillary zone (inner region)
Ciliary zone (outer region)
Iris Root
The lens
Lens Capsule
Thick, elastic basement membrane
Made primarily of type IV collagen and laminin
Transparent and acellular
Acts as an anchor for zonular fibers (suspensory ligaments)
Participates in accommodation (focusing changes)
The capsule is thicker at the front (anterior capsule) and thinner at the back (posterior capsule)
Anterior Lens Epithelium
Structure:
Single layer of cuboidal epithelial cells
Only living, mitotically active cells in the lens
Function:
Produces new lens fiber cells
Regulates ion and water balance
Maintains transparency through active transport
These cells migrate toward the equator and differentiate into fiber cells.
Lens Fibers
Structure:
Long, thin, transparent cells
Packed tightly in concentric layers
Lose their nuclei and organelles as they mature
mature lens fibers have no nucleus, no mitochondria, no ER.
Function:
Create refractive power
Maintain transparency
Provide structural integrity
Cortex
cortex is the outer region of lens fibers.
This region plays a major role in accommodation
Nucleus
the central core of the lens.
we age, the nucleus hardens (nuclear sclerosis), reducing accommodation
Lens Sutures
fiber cells meet at the poles
Structure:
Y-shaped patterns (upright Y anteriorly, inverted Y posteriorly)
Lens Poles and Equator
Anterior pole:
Front center of lens.
Posterior pole:
Back center.
Equator:
Widest circumference, where new fiber cells form.
Internal Microstructure
Inside lens fibers:
High concentration of crystallin proteins
Alpha crystallins (chaperone-like function)
Beta and gamma crystallins (structural transparency)
Crystallins are extremely stable proteins that must last a lifetime.
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Book 2
Plasma Membrane
The Gated City
Reality Exists In Layers
The outermost layer being like a shell. Micro beings, people and beasts move busy as the gatekeepers watch who moved into the deeper layers of existence. This city feels crowded with a thin atmosphere and far from its first star: the Nucloendo seed. This is the place for level zero souls. Everyone starts in the matrix as the environment holds its creations in suspension.
Imagine. A field where the bodies of advanced beings you have never known, people and animals while there exists a bubble barrier around them. This bubble is the surface realm and it’s environment is static and charged.
There exists 22 possibilities for life on the surface to go through. Life on the surface is short so it’s expected to make this time as eventful and meaningful as possible.
The encounters creatures face, their actions and reactions create a scaffold of their character. While the environment itself does the same. This scaffold will be used repeatedly throughout the building of the 22.
The separation into 22 possibilities help people and animals find one another and allowing the movement from an overcrowded surface into a more relaxed space. Structures built for each species “Type”. Reactions between the scaffolds happen as they conflict with each other.
This conflicting attracts the attention of Nuclumito the migrating seed as it packs away the differences to carry through Ixchel
The 22 destinations are as follows:
tRNA^Met AUG (start codon)
A precursor
Part With Part Of Yourself
When someone enters this realm they are to give up a part of their life experience to a targeted scaffold. Building the world around them using a part of themselves. That piece of themselves will grow the world around them. This however is not a random act, there’s a process to place the piece of scaffold where it’s best suited to fit. It can change how Ixchel is experienced in the future.
There are four structures in this realm and four types of scaffold to contribute. To build with the scaffold is to “bridge” the pieces until it’s seen that everything is connected. Nuclumito likes to fill in the gaps.
There exists in this realm four orbs of light types at the top of four stone tablets. Information from the scaffolds get compressed into an orb and that orb represents a miniature star. What is part of the big picture is first practiced here.
Everyone is capable of producing an orb of light but not all can exist together at once. So for some the light is turned off and their light get ignored temporarily to maintain the identity of the realm. That being expressed visually as an animal constellation where certain stars are “silenced” and others “activated” to maintain the form of the animal as it becomes an animation in the sky through this process.
This animation is offered as a gift, carried through generations, the maintained patterns are added to each new phase of existence.
Conceal Your Inquiry
There are also what is called an “empty” star. These stars are a wrapped up mystery. A question, and Nuclumito likes to get creative here to make something that hasn’t existed before.
The first constellation to be created is full of these “empty” stars, full of questions dressed in information. It doesn’t ask to be answered directly but instead is built on the information that has been attached to it.
Important for gene silencing and epigenetics.
your DNA letters (A, T, C, G) stay the same, but certain genes are turned on or off
usually happen through chemical tags on DNA or histone proteins
Histone methyltransferases (HMTs)
Add methyl groups to histone proteins, affecting chromatin structure.
RNA methyltransferases
Modify RNA to control stability and translation
one carbon atom bonded to three hydrogen atoms (–CH₃).
Methyl donors give their methyl group to other molecules, often using enzymes called methyltransferases.
methylation Is the process of adding a methyl group (–CH₃) to a molecule
Also
Cysteine (via the transsulfuration pathway)
Methionine → homocysteine → cysteine
Cysteine is important for glutathione synthesis (major antioxidant)
And
Polyamines
tRNA^Met UAC,AUG
tRNA^Phe Recognizes UUU, UUC
tRNA^Val GUU, GUC, GUA, GUG
tRNA^Leu(UUR) UUA, UUG
tRNA^Leu(CUN) CUU, CUC, CUA, CUG
tRNA^Ile AUU, AUC, AUA
tRNA^Trp UGG
tRNA^Ala GCU, GCC, GCA, GCG
tRNA^Asn AAU, AAC
tRNA^Cys UGU, UGC
tRNA^Tyr UAU, UAC
tRNA^Ser(UCN) UCU, UCC, UCA, UCG
tRNA^Ser(AGY) AGU, AGC
tRNA^Glu GAA, GAG
tRNA^Gln CAA, CAG
tRNA^Pro CCU, CCC, CCA, CCG
tRNA^His CAU, CAC
tRNA^Arg CGU, CGC, CGA, CGG, AGA, AGG
tRNA^Thr ACU, ACC, ACA, ACG
tRNA^Gly GGU, GGC, GGA, GGG
tRNA^Lys AAA, AAG
tRNA^Asp GAU, GAC
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Book 2:2
From the external environment (extracellular space)
main role:
Control what enters and exits the cell, while supporting communication and structure
Structure:
Lipid Bilayer
Made mainly of phospholipids
Phospholipids are amphipathic:
Hydrophilic head → faces water inside and outside
Hydrophobic tail → faces inward, away from water
Forms a semi-permeable barrier:
Lets some molecules (like gases) pass freely
Restricts ions and large molecules
Proteins
Integral (transmembrane) proteins:
Serve as channels, transporters, or receptors
Peripheral proteins:
Attach to the membrane surface
Provide structure, signaling, or anchor points
Carbohydrates
Often attached to proteins (glycoproteins) or lipids (glycolipids)
Functions:
Cell recognition
Signaling
Protection
Cholesterol
Inserts between phospholipids
Modulates fluidity and stability
Characteristics
Selectively Permeable
Fluid Mosaic
Membrane components are not static
Lipids and proteins can move laterally
Dynamic and Asymmetric
Different lipids/proteins on inner vs outer leaflet
Asymmetry allows specialized functions like signaling or endocytosis
Barrier and Gateway
Receptors detect hormones, neurotransmitters, or signals
Adhesion
Links to other cells and extracellular matrix
Signal Transduction
Converts external signals into intracellular responses
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Book 3
Nucleus
Chromatin
Complex of DNA and proteins (mainly histones)
Exists in two forms:
Euchromatin
Heterochromatin
During cell division, chromatin condenses into chromosomes
Nucleolus
Produces ribosomal RNA (rRNA) and assembles ribosome subunits.
Nuclear Matrix
Types
Polyploid nuclei
Multinucleated cells (syncytial nuclei)
Micronuclei
Amitotic nuclei
Euchromatic nuclei
heterochromatic
Supraoptic nucleus → Produces ADH
Paraventricular nucleus → Produces oxytocin & other hormones
Arcuate nucleus → Controls hormone release & appetite
Ventromedial nucleus → “Satiety center” (fullness)
Lateral hypothalamus → “Hunger center”
Mammillary bodies → Memory processing
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Book 4
Mitochondria
Outer Membrane
Contains protein channels called porins
Intermembrane Space
Plays a key role in oxidative phosphorylation, as protons (H⁺) are pumped here during electron transport to create a proton gradient.
Inner Membrane
Highly folded into cristae, which increase surface area.
Contains electron transport chain proteins and ATP synthase
Cristae
Matrix
Contains mitochondrial DNA (mtDNA), ribosomes, enzymes for the Krebs cycle, and tRNA.
site of the Krebs cycle (citric acid cycle) and other metabolic reactions.
Mitochondrial DNA (mtDNA)
Ribosomes
ATP Synthase
converts ADP + Pi into ATP
