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🧱 Cellular Structures (Organelles & Architecture)

Mitochondria

Phospholipid bilayer

Cardiolipin

Cytochrome c

Nuclear-encoded mitochondrial proteins

Bcl-2 family proteins

Porins (VDAC – Voltage-Dependent Anion Channels)

Ribosomes

Apoptosis signaling factors

β-oxidation enzymes

Pyruvate dehydrogenase complex

NADH/FADH₂ production

Complex II (succinate dehydrogenase)

Complex I (NADH dehydrogenase)

Complex III (cytochrome bc1)

Complex IV (cytochrome c oxidase)

TOM Complex (Translocase of the Outer Membrane)

Electron Transport Chain (ETC)

Citric Acid Cycle (Krebs Cycle)

Cristae

Intermembrane Space (IMS)

Outer Mitochondrial Membrane (OMM)

Inner Mitochondrial Membrane (IMM)

Mitochondrial Matrix

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🧱 Cellular Structures (Organelles & Architecture)

Nucleus

linker DNA

Histones in

nuclear localization signals (NLS)

lamins (A, B, C)

Intermediate filament proteins

Transcription factors in

Outer Nuclear Membrane (ONM)

Inner Nuclear Membrane (INM)

transmembrane proteins

rough endoplasmic reticulum (RER)

ER lumen

cytoplasmic surface

Perinuclear Space

Nucleosome (Basic Unit)

Euchromatin

Heterochromatin

chromatin

nuclear lamina

LINC complexes

Nuclear Pore Complexes (NPCs)

nucleoporins

octagonal structure

Central transport channel

Cytoplasmic filaments

Nuclear basket

mRNA out

Ribosomal subunits out

gene regulation

nuclear organization

🧱 Cellular Structures (Organelles & Architecture)

Nucleolus

rRNA transcription (by RNA polymerase I)

snRNP maturation

40S

60S

Ribosomal subunit assembly

Fibrillar center (FC)

Dense fibrillar component (DFC)

Granular component (GC)

Replication foci

DNA repair centers

Transcription factories (RNA polymerase clusters)

Cajal Bodies

PML Bodies

Speckles

Topologically associating domains (TADs)

Lamina-associated domains (LADs)

Chromosome Territories

🧠 Neural Developmental Lineage

Neuroepithelial Cells

Neural tube

Apical surface

True Epithelium

Apical–basal polarity

Mitosis

Symmetric Proliferation / symmetric division (expansion)

Ventricular zones

Interkinetic Nuclear Migration

Asymmetric division (neuron production)

🧠 Neural Developmental Lineage

Radial Glial Cells

Ventricular Zone

Apical Process

Apical Endfoot

Basal Process

Radial Fiber

Apical–Basal Polarity

Stem Cell / Progenitor Function

Scaffolding Function for Neuron Migration

Dynamic Interkinetic Nuclear Migration

🧠 Neural Developmental Lineage

Intermediate Progenitor Cells

Subventricular Zone (SVZ)

Apical Polarity

Basal Polarity

Symmetric Division Machinery

Transient Stem-Like State

Delamination

Scaffold

Basal Process

Rapid Neurogenic Output

🧠 Neural Developmental Lineage

Basal Progenitor Cells

Apical Polarity

Basal Polarity

Transient Progenitor Identity

Delamination from Ventricular Zone

Process

Scaffold

Neurogenic Output

Cortical Development Signals

🧠 Neural Developmental Lineage

Astrocyte Progenitor Cells

Germinal Zones

White Matter

Glial Lineage Commitment

Apical Polarity

Basal Polarity

Proliferative Capacity

Astrocytic Markers

Gliogenic Signals

Astrocytic Morphology

Astrocytic Morphology Transition

Postnatal Glial Networks

🧠 Neural Developmental Lineage

Oligodendrocyte Precursor Cells

Oligodendrocyte Lineage Commitment

Multipolar Morphology

OPC pool

OPC-Specific Markers

OPC-Specific Markers Expression

Migration

Mature Myelinating Oligodendrocytes

🔁 Programmed Cellular Processes

Interphase: G₁ Phase (Gap 1)

Cytoplasmic Growth

Organelle Duplication

Preparation

RNA Synthesis

Protein Synthesis

Transcription Activation

Translation

Growth Factor Detection

Signal Transduction

Cyclin Synthesis

R-Point (Restriction Point)

DNA Damage Monitoring

p53

Repair Activation

NER (nucleotide excision repair)

BER (base excision repair)

🔁 Programmed Cellular Processes

S Phase (Synthesis)

Origin Recognition Complex (ORC)

MCM helicase

Helicase Activation

Single-Strand Binding

Replication Protein A (RPA)

RNA Primer Synthesis

Primase

DNA polymerase α complex

Leading Strand

DNA polymerase ε

Lagging Strand

Okazaki fragments

DNA polymerase δ

RNase H

FEN1

Gap Filling

DNA ligase I

Proofreading

Mismatch Repair

Replication Fork Dynamics

Checkpoint Surveillance: ATR Pathway

CHK1 pathway

Fork Convergence

Decatenation

Topoisomerase II

🔁 Programmed Cellular Processes

G₂ Phase (Gap 2)

Protein Synthesis

Organelle Synthesis

Organelle Maturation

Microtubule Network

Actin Network

Replication Verification

DNA repair pathways

mismatch repair (MMR)

double-strand break repair

Cyclin B Accumulation

Cyclin B-CDK1 complexes

Mitotic Entry Activation

G₂/M Checkpoint

ATM Proteins

ATR Proteins

p53

CHK1

CHK2

Spindle Pole Body Duplication

Centrosome Maturation

Nuclear lamina

🔁 Programmed Cellular Processes

Meiosis I: Prophase I

Chromatin Condensation

Centrosome Duplication

Centrosomes

Spindle Formation

Spindle fibers

Synapsis Initiation

Homologs

Synaptonemal Complex Formation

Protein scaffold

Recombination

Programmed double-strand breaks (DSBs)

Spo11 enzyme

Homologous recombination

non-sister chromatids

Chiasmata Formation

Late Prophase I / Diplotene

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