First World Judgment

A costly misconception of Lamina as the Voices try to interpret a new universe with an old way of thinking. 

They see the Lumine and the Laminae as oppressed beings in a place of psychological torment that. The the Opsin Rings are holding them captive and they need to be “liberated”

The reality is that the Voices know nothing about the cultures and their actions may be deadly

The universe has decided to allow this because of the potential and opportunities that are a product of this mistake. 

This misjudgment is an important moment in history and has been named “Uniform 33”

Uniform 33

The Lumine and the Laminae will face difficult times as a reaction to the Voices' assumption. Their existence has restrictions, although it’s misunderstood as a punishment by the Voices.

In the uninformed state, it appears as a prison, inhabited by people who have committed no crimes.

Rules: Ultraviolet Ring

Small, rigid, a realm that is in the Ultraviolet spectrum. During this time the realm demands uniformity and breeds apathy. For the most part, the Lumine are invisible.

Only twelve are allowed to take form at a time. Without form they are unable to be seen or communicate. They are prohibited from having names and their voice is monotone without sounding male or female.

Rules: Infrared Ring

It exists in two stages: “Compact Stage” and the “Extended Stage.”

Made of 22 tRNAs forced to work in the form of 11 phases.

In the “Compact Stage” two realities are being experienced simultaneously because the space has been compressed.

Rules: Both Rings

The people are to eventually recognize the universal truth as the anchor between creativity and chaos. The Voices see this universal truth as an oppressive one-world religion. Upon the arrival of the Voices, this anchor gets removed and the Voices try to put their own views into the world.

Meaning

The meaning behind Uniform 33 is a reflection on mental illness. Not experienced as an individual but instead, by the entire population. The Ultraviolet Ring touches on the loss of identity and the rise of apathy, the feeling of losing oneself. Meanwhile, the Infrared Ring focuses on the existence of two realities that appear simultaneously with one left to decipher.

The Problem

There is an issue with the Opsin Portal and its rings: the rings have been compressed into 33 pieces, causing dimensions to overlap. What does this mean? It will be revealed by Nuclumito. 

Sequence 33

The Opsin Rings are in place. The ultraviolet ring and the infrared ring to be read by Nuclumito

A very important part of Lamina is the Opsin Portal. It’s made of two flat rings stacked on top of each other while Nuclumito, the migrating seed reads the information from both rings. One ring has 11 sections, resembling mtDNA genes but smaller and more universal. While the other ring has 22 sections.

Concept Of Creation

The Lumine and the Laminae do not necessarily have a religion but they believe in a creator. The spark of light in the darkest of darkness. Without a physical body, however, with the nature of the body. A force that was always present and the inventor of light which later became light. It serves as the anchor that keeps creation together. The difference between creativity and lawlessness. Not moral lawlessness but instead quite literally. It’s universally recognized but not worshipped and is about as arguable as gravity.

Falling Into Void

A painful trip taken to open the Lamina Pathway to make way for the Nucloendo Seed to emerge and create a star.

These stars make up animal constellations of stars connected by synapses

FGF → MAPK/ERK activation

(canonical pathway)

FGF binds its receptor (FGFR)

FGF (Fibroblast Growth Factor) is a family of secreted signaling proteins that act as growth factors

They tell cells when to divide, survive, migrate, or differentiate,

There are 22 FGFs in humans

Core properties of FGF

It is a ligand

extracellular proteins that bind to FGF receptors (FGFR1–FGFR4) on the cell surface

It signals through FGFR (a receptor tyrosine kinase)

FGFs bind FGFR

Binding causes receptor dimerization

FGFRs autophosphorylate tyrosine residues

Heparan sulfate–dependent

FGF (Fibroblast Growth Factor) is a ligand

binds to FGFR, a receptor tyrosine kinase (RTK) on the cell membrane

Binding causes FGFR dimerization (two receptors pair up)

The paired FGFRs phosphorylate each other

on specific tyrosine residues

These phosphotyrosines become docking sites for adaptor proteins

Adaptor proteins assemble (FGFR → FRS2)

FRS2 (FGF Receptor Substrate 2) binds to the activated FGFR

FGFR phosphorylates FRS2

Phosphorylated FRS2 recruits:

Grb2

SOS (a guanine nucleotide exchange factor)

SOS activates RAS by swapping:

GDP → GTP

RAS-GTP is now active

RAF activation

Active RAS recruits RAF to the membrane

RAF becomes activated

MEK activation

RAF phosphorylates MEK

ERK activation

MEK phosphorylates ERK

the core MAPK cascade: 

RAF → MEK → ERK

ERK enters the nucleus

Activated ERK moves into the nucleus

ERK phosphorylates transcription factors such as:

ELK1

c-Fos

c-Myc

two FGFR molecules pair up

FGFR Autophosphorylation

The FGFR receptors phosphorylate each other

Adapter Protein Grb2 Binds

Grb2 recruits SOS, a guanine nucleotide exchange factor (GEF).

Ras Becomes Active

SOS activates Ras by helping it exchange GDP for GTP.

Ras-GDP (inactive) → Ras-GTP (active)

Ras Activates Raf

Activated Ras binds and activates Raf

Raf Activates MEK

Raf phosphorylates and activates MEK.

MEK Activates ERK

MEK phosphorylates and activates ERK (MAPK)

ERK Enters the Nucleus

Activated ERK moves into the nucleus and activates transcription factors.

A Pit Of Seeds

Leaving the old universe behind, the path will be extreme as the new universe is built from the ground.

Six types of seeds exist as the people willingly “fall” in order to plant them

Two seeds were given names:

Nuclumito - Seed of mitochondria

Nucloendo - Seed of nucleolus

“Empty” Seeds

Empty seeds are a shrouded mystery, an inquiry wrapped in information

Matrix Mechanism

In the early days of Lamina a matrix was created. To serve as a universal guide on how to navigate this new universe.

The two rings exist mtDNA and tRNA

The top ring made of 11 mtDNA’s and the bottom ring made of 22 tRNA’s

In between these rings there is a multidimensional rainbow space called Ixchel that serves as the environment.

Along with it is the migrating seed called Nuclumito. Appearing as a black sphere it absorbs the information from the two rings and reads the sequence.

Once the sequence has been read the information, it is then compressed. Going from being a chunk of information into a short as possible piece of imagery.

Now it’s time to create stars (tightly compressed information) and threads (synapses)

Creating a constellation of an animal with 13 stars and 22 threads

Lamina Pathway

The Lamina Pathway is a tube lined with cells (neural tube). As information passes through it becomes influenced by these cells.

The creativity pool exists at the bottom. It serves as reserve to gather pieces of information turn it into an environment of two polar opposite realities. 

The information is held together with a scaffold of communications between synapses.

Leaving The Matrix

A Lumine and a Laminae are free to leave the matrix but, first they need to break uniformity. Meaning they need to absorb the features of the animal they feel a deep connection with.

They enter the realms:

Alpha, Beta and Delta

These are the three anchors that make the difference between creativity and chaos

Asymmetric division → Radial glial progenitor + one anchor

Dracae (The Tree Of Wisdom)

In the middle of Alpha, Beta and Delta, the Dracae processes the knowledge written in the creatures. A structure of 5 rings. Two for the animal and three for the plant. 

The animals can be experienced.

Mitochondrial DNA, Nuclear DNA, Chloroplast DNA

Real Animals

Big Cats

Tiger - Panthra

Lion

Leopard

Cheetah - Acino

Jaguar - yagouaru

Snow Leopard

Cougar

Lynx

Caracal

Serval - Leptai

Ocelot - pardali

Wolves

Arctic wolf

Timber wolf - baileyi

Mongolian wolf

Iberian wolf - Sinatu 

Red Wolf

Ethiopian Wolf - simen

Dingo

Jackal - aureus

Coyote

Foxes

Red fox - Vul

Arctic fox 

Fennec fox - zerda

Kit fox

Gray fox - Uroc